Human ANTXR1/TEM8 protein (Recombinant-Active) (C-His) (STJP012266)

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STJP012266-100
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human ANTXR1/TEM8-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: ANTXR1
Gene ID: 84168
Uniprot ID: ANTR1_HUMAN
Immunogen Region: Glu33-Ser321
Immunogen: Homo sapiens (Human)
Function Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells. (Microbial infection) Acts as a receptor for protective antigen (PA) of B.anthracis.
Protein Name Anthrax Toxin Receptor 1
Tumor Endothelial Marker 8
Database Links Reactome: R-HSA-5210891
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Projection
Lamellipodium Membrane
Filopodium Membrane
At The Membrane Of Lamellipodia And At The Tip Of Actin-Enriched Filopodia
Colocalizes With Actin At The Base Of Lamellipodia
Alternative Protein Names Anthrax Toxin Receptor 1 protein
Tumor Endothelial Marker 8 protein
ANTXR1 protein
ATR protein
TEM8 protein

Information sourced from Uniprot.org

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