| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 0.01 EU/Mu g of the protein by LAL method. |
| Gene Symbol: | AMHR2 |
| Gene ID: | 269 |
| Uniprot ID: | AMHR2_HUMAN |
| Immunogen Region: | Pro18-Ser144 |
| Immunogen: | Recombinant Human AMHR2/MISR2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Pro18-Ser144) of Human AMHR2/MISR2 (Accession #Q16671) fused with a hFC tag at the C-terminus. |
| Immunogen Sequence: | MQLKPMEINPEMLNKVLSRL GVAGQWRFVDVLGLEEESLG SVPAPACALLLLFPLTAQHE NFRKKQIEELKGQEVSPKVY FMKQTIGNSCGTIGLIHAVA NNQDKLGFEDGSVLKQFLSE TEKMSPEDRAKCFEKNEAIQ AAHDAVAQEGQCRVDDKVNF HFILFNNVDGHLYELDGRMP FPVNHGASSEDTLLKDAAKV CREFTEREQGEVRFSAVALC KAA |
| Function | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. |
| Protein Name | Anti-Muellerian Hormone Type-2 ReceptorAnti-Muellerian Hormone Type Ii ReceptorAmh Type Ii ReceptorMis Type Ii ReceptorMisriiMrii |
| Database Links | Reactome: R-HSA-201451 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Anti-Muellerian Hormone Type-2 Receptor proteinAnti-Muellerian Hormone Type Ii Receptor proteinAmh Type Ii Receptor proteinMis Type Ii Receptor proteinMisrii proteinMrii proteinAMHR2 proteinAMHR proteinMISR2 protein |
Information sourced from Uniprot.org