| Short Description : | Recombinant-Human Alpha 1-Acid Glycoprotein 1/ORM1-His-Tag protein was developed from hek293 cells and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE |
| Host: | HEK293 Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 1 mg/mL |
| Formulation: | Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin: | < 1 EU per 1ug of protein (determined by LAL method) |
| Gene Symbol: | ORM1 |
| Gene ID: | 5004 |
| Uniprot ID: | A1AG1_HUMAN |
| Accession Number: | NP_000598.2 |
| Immunogen: | Human |
| Immunogen Region: | 19-201aa |
| Immunogen Sequence: | QIPLCANLVP VPITNATLDR ITGKWFYIAS AFRNEEYNKS VQEIQATFFY FTPNKTEDTI FLREYQTRQD QCIYNTTYLN VQRENGTISR YVGGQEHFAH LLILRDTKTY MLAFDVNDEK NWGLSVYADK PETTKEQLGE FYEALDCLRI PKSDVVYTDW KKDKCEPLEK QHEKERKQEE GES |
| Tissue Specificity | Expressed by the liver and secreted in plasma. |
| Post Translational Modifications | N-glycosylated. N-glycan heterogeneity at Asn-33: Hex5HexNAc4 (minor), Hex6HexNAc5 (major) and dHex1Hex6HexNAc5 (minor). |
| Function | Functions as a transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction. |
| Protein Name | Alpha-1-Acid Glycoprotein 1Agp 1Orosomucoid-1Omd 1 |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-6798695 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Alpha-1-Acid Glycoprotein 1 proteinAgp 1 proteinOrosomucoid-1 proteinOmd 1 proteinORM1 proteinAGP1 protein |
Information sourced from Uniprot.org
