Human Aldolase A/ALDOA protein (Recombinant) (His-Tag) (STJP016618)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP016618
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General Information

Short DescriptionRecombinant-Human Aldolase A/ALDOA-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE/Enzyme Activity
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration1 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.0) containing 100mM NaCl, 10% Glycerol
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
ImmunoreactivitySpecific activity is > 10unit/mg, one unit will convert 1.0 umol of fructose 1, 6-diphosphate to dihydroxyacetone phosphate and glyceraldehydes 3-phosphate per minute at pH 7.5 at 37C.

Target Information

Gene SymbolALDOA
Gene ID226
Uniprot IDALDOA_HUMAN
Accession NumberNP_908930
ImmunogenHuman
Immunogen Region1-364aa
Immunogen Sequence MPYQYPALTP EQKKELSDIA HRIVAPGKGI LAADESTGSI AKRLQSIGTE NTEENRRFYR QLLLTADDRV NPCIGGVILF HETLYQKADD GRPFPQVIKS KGGVVGIKVD KGVVPLAGTN GETTTQGLDG LSERCAQYKK DGADFAKWRC VLKIGEHTPS ALAIMENANV LARYASICQQ NGIVPIVEPE ILPDGDHDLK RCQYVT

Additional Info

Function Catalyzes the reversible conversion of beta-D-fructose 1,6-bisphosphate (FBP) into two triose phosphate and plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein.
Protein Name Fructose-Bisphosphate Aldolase A
Lung Cancer Antigen Ny-Lu-1
Muscle-Type Aldolase
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-6798695
Reactome: R-HSA-70171
Reactome: R-HSA-70263
Cellular Localisation Cytoplasm
Myofibril
Sarcomere
I Band
M Line
In Skeletal Muscle
Accumulates Around The M Line And Within The I Band
Colocalizing With Fbp2 On Both Sides Of The Z Line In The Absence Of Ca(2+)
Alternative Protein Names Fructose-Bisphosphate Aldolase A protein
Lung Cancer Antigen Ny-Lu-1 protein
Muscle-Type Aldolase protein
ALDOA protein
ALDA protein

Information sourced from Uniprot.org

Citations

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