Human ALDOB (Aldolase B, Fructose Bisphosphate) Sandwich ELISA Kit (STJE0007064)
SPECIFICATIONS
General Information
| Short Description | This ALDOB Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.063ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | ALDOB |
| Gene ID | 229 |
| Uniprot ID | ALDOB_HUMAN |
| Sample Type | serum, plasma, tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Catalyzes the aldol cleavage of fructose 1,6-biphosphate to form two triosephosphates dihydroxyacetone phosphate and D-glyceraldehyde 3-phosphate in glycolysis as well as the reverse stereospecific aldol addition reaction in gluconeogenesis. In fructolysis, metabolizes fructose 1-phosphate derived from the phosphorylation of dietary fructose by fructokinase into dihydroxyacetone phosphate and D-glyceraldehyde. Acts as an adapter independently of its enzymatic activity, exerts a tumor suppressor role by stabilizing the ternary complex with G6PD and TP53 to inhibit G6PD activity and keep oxidative pentose phosphate metabolism in check. |
| Protein Name | Fructose-Bisphosphate Aldolase BLiver-Type Aldolase |
| Database Links | Reactome: R-HSA-5657560Reactome: R-HSA-70171Reactome: R-HSA-70263Reactome: R-HSA-70350 |
| Cellular Localisation | CytoplasmCytosolCytoskeletonMicrotubule Organizing CenterCentrosomeCentriolar Satellite |
| Alternative ELISA Names | Fructose-Bisphosphate Aldolase B ELISA kitLiver-Type Aldolase ELISA kitALDOB ELISA kitALDB ELISA kit |
| output |
Information sourced from Uniprot.org