Human AKR1D1 protein (Recombinant) (N-His) (STJP015787)

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STJP015787
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Short Description :Recombinant-Human AKR1D1-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:Please contact us for further information.
Gene Symbol:AKR1D1
Gene ID:6718
Uniprot ID:AK1D1_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Met1-Tyr326
Function Catalyzes the stereospecific NADPH-dependent reduction of the C4-C5 double bond of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure to yield an A/B cis-ring junction. This cis-configuration is crucial for bile acid biosynthesis and plays important roles in steroid metabolism. Capable of reducing a broad range of delta-(4)-3-ketosteroids from C18 (such as, 17beta-hydroxyestr-4-en-3-one) to C27 (such as, 7alpha-hydroxycholest-4-en-3-one).
Protein Name Aldo-Keto Reductase Family 1 Member D1
3-Oxo-5-Beta-Steroid 4-Dehydrogenase
Delta(4-3-Ketosteroid 5-Beta-Reductase
Delta(4-3-Oxosteroid 5-Beta-Reductase
Database Links Reactome: R-HSA-193368
Reactome: R-HSA-193775
Reactome: R-HSA-193807
Cellular Localisation Cytoplasm
Alternative Protein Names Aldo-Keto Reductase Family 1 Member D1 protein
3-Oxo-5-Beta-Steroid 4-Dehydrogenase protein
Delta(4-3-Ketosteroid 5-Beta-Reductase protein
Delta(4-3-Oxosteroid 5-Beta-Reductase protein
AKR1D1 protein
SRD5B1 protein

Information sourced from Uniprot.org

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