Function | Targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium. |
Protein Name | A-Kinase Anchor Protein 7 Isoforms Alpha And BetaAkap-7 Isoforms Alpha And BetaA-Kinase Anchor Protein 18 KdaAkap 18Protein Kinase A-Anchoring Protein 7 Isoforms Alpha/BetaPrka7 Isoforms Alpha/Beta |
Cellular Localisation | Isoform Alpha: Lateral Cell MembraneLipid-AnchorTargeted Predominantly To The Lateral MembraneIsoform Beta: Apical Cell MembraneTargeted Predominantly To The Apical Membrane |
Alternative Protein Names | A-Kinase Anchor Protein 7 Isoforms Alpha And Beta proteinAkap-7 Isoforms Alpha And Beta proteinA-Kinase Anchor Protein 18 Kda proteinAkap 18 proteinProtein Kinase A-Anchoring Protein 7 Isoforms Alpha/Beta proteinPrka7 Isoforms Alpha/Beta proteinAKAP7 proteinAKAP15 proteinAKAP18 protein |
Information sourced from Uniprot.org