Human AK1 protein (Recombinant) (His-Tag) (STJP016909)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP016909
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General Information

Short DescriptionRecombinant-Human AK1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE/Enzyme Activity
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration1 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 7.5) containing 10% Glycerol
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
ImmunoreactivitySpecific activity: > 600unit/mg. One unit will convert 2.0 umoles of ADP to ATP + AMP per minute at pH 7.5 at 37C.

Target Information

Gene SymbolAK1
Gene ID203
Uniprot IDKAD1_HUMAN
Accession NumberNP_000467
ImmunogenHuman
Immunogen Region1-194aa
Immunogen SequenceMGSSHHHHHH SSGLVPRGSH MEEKLKKTKI IFVVGGPGSG KGTQCEKIVQ KYGYTHLSTG DLLRSEVSSG SARGKKLSEI MEKGQLVPLE TVLDMLRDAM VAKVNTSKGF LIDGYPREVQ QGEEFERRIG QPTLLLYVDA GPETMTQRLL KRGETSGRVD DNEETIKKRL ETYYKATEPV IAFYEKRGIV RKVNAEGSVD SVFSQVCTHL DALK

Additional Info

Function Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Also catalyzes at a very low rate the synthesis of thiamine triphosphate (ThTP) from thiamine diphosphate (ThDP) and ADP.
Protein Name Adenylate Kinase Isoenzyme 1
Ak 1
Atp-Amp Transphosphorylase 1
Atp -Amp Phosphotransferase
Adenylate Monophosphate Kinase
Myokinase
Database Links Reactome: R-HSA-499943
Cellular Localisation Cytoplasm
Alternative Protein Names Adenylate Kinase Isoenzyme 1 protein
Ak 1 protein
Atp-Amp Transphosphorylase 1 protein
Atp -Amp Phosphotransferase protein
Adenylate Monophosphate Kinase protein
Myokinase protein
AK1 protein

Information sourced from Uniprot.org

Citations

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