SDS-PAGE of recombinant human AgRP protein 3µg under reducing conditions stained with Coomassie blue

Human AgRP protein (Recombinant) (His-Tag) (STJP019105)

SKU:
STJP019105
£130.50 - £545.50
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Short Description :Recombinant-Human AgRP-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.25 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.5) containing 20% Glycerol, 1mM DTT
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:AGRP
Gene ID:181
Uniprot ID:AGRP_HUMAN
Accession Number:NP_001129
Immunogen:Human
Immunogen Region:21-132aa
Immunogen Sequence:AQMGL APMEGIRRPD QALLPELPGL GLRAPLKKTT AEQAEEDLLQ EAQALAEVLD LQDREPRSSR RCVRLHESCL GQQVPCCDPC ATCYCRFFNA FCYCRKLGTA MNPCSRT
Tissue Specificity Expressed primarily in the adrenal gland, subthalamic nucleus, and hypothalamus, with a lower level of expression occurring in testis, lung, and kidney.
Function Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin system. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R. Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner.
Protein Name Agouti-Related Protein
Database Links Reactome: R-HSA-9615017
Cellular Localisation Secreted
Golgi Apparatus Lumen
Alternative Protein Names Agouti-Related Protein protein
AGRP protein
AGRT protein
ART protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP003138 Human AGRP protein (Recombinant) (N-His) (STJP003138) E.coli ELISA/Immunogen/SDS-PAGE/WB
STJP019690 Human IRF2 protein (Recombinant) (His-Tag) (STJP019690) E.coli SDS-PAGE
STJP017768 Human CSTF1 protein (Recombinant) (His-Tag) (STJP017768) E.coli SDS-PAGE/Denatured
STJP017869 Human RNF4 protein (Recombinant) (His-Tag) (STJP017869) E.coli SDS-PAGE
STJP017870 Human NDUFA5 protein (Recombinant) (His-Tag) (STJP017870) E.coli SDS-PAGE

Related Products

!