Human AG-2/AGR2 protein (Recombinant) (His-Tag) (STJP016413)

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STJP016413
£134.50 - £738.50
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human AG-2/AGR2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 1mM EDTA
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: AGR2
Gene ID: 10551
Uniprot ID: AGR2_HUMAN
Immunogen Region: 21-175aa
Accession Number: NP_006399.1
Immunogen: Human
Immunogen Sequence: RDTT VKPGAKKDTK DSRPKLPQTL SRGWGDQLIW TQTYEEALYK SKTSNKPLMI IHHLDECPHS QALKKVFAEN KEIQKLAEQF VLLNLVYETT DKHLSPDGQY VPRIMFVDPS LTVRADITGR YSNRLYAYEP ADTALLLDNM KKALKLLKTE L
Tissue Specificity Expressed strongly in trachea, lung, stomach, colon, prostate and small intestine. Expressed weakly in pituitary gland, salivary gland, mammary gland, bladder, appendix, ovary, fetal lung, uterus, pancreas, kidney, fetal kidney, testis, placenta, thyroid gland and in estrogen receptor (ER)-positive breast cancer cell lines.
Function Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells. Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth. Promotes cell adhesion.
Protein Name Anterior Gradient Protein 2 Homolog
Ag-2
Hag-2
Hpc8
Secreted Cement Gland Protein Xag-2 Homolog
Database Links
Cellular Localisation Secreted
Endoplasmic Reticulum
Alternative Protein Names Anterior Gradient Protein 2 Homolog protein
Ag-2 protein
Hag-2 protein
Hpc8 protein
Secreted Cement Gland Protein Xag-2 Homolog protein
AGR2 protein
AG2 protein
UNQ515 protein
PRO1030 protein

Information sourced from Uniprot.org

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