Human AFAP1 protein (Recombinant) (N-His) (STJP009669)

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STJP009669
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human AFAP1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: AFAP1
Gene ID: 60312
Uniprot ID: AFAP1_HUMAN
Immunogen Region: Glu346-Ile478
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylated on tyrosine residues by SRC.
Function Can cross-link actin filaments into both network and bundle structures. May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells.
Protein Name Actin Filament-Associated Protein 1
110 Kda Actin Filament-Associated Protein
Afap-110
Cellular Localisation Cytoplasm
Cytoskeleton
Stress Fiber
Alternative Protein Names Actin Filament-Associated Protein 1 protein
110 Kda Actin Filament-Associated Protein protein
Afap-110 protein
AFAP1 protein
AFAP protein

Information sourced from Uniprot.org

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