Human Afamin/AFM protein (Recombinant) (C-His) (STJP002838)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human Afamin/AFM Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Asn599) of human Afamin/AFM (Accession #NP_001124.1) fused with and a 6×His tag at the C-terminus.
General Information
| Short Description | Recombinant-Human Afamin/AFM-C-His protein was developed in hek293 cells using the region Met1-Asn599. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | <0.1 EU/Mu g |
Target Information
| Gene Symbol | AFM |
| Gene ID | 173 |
| Uniprot ID | AFAM_HUMAN |
| Immunogen | Recombinant Human Afamin/AFM Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Asn599) of human Afamin/AFM (Accession #NP_001124.1) fused with and a 6×His tag at the C-terminus. |
| Immunogen Region | Met1-Asn599 |
| Immunogen Sequence | MKLLKLTGFIFFLFFLTESL TLPTQPRDIENFNSTQKFIE DNIEYITIIAFAQYVQEATF EEMEKLVKDMVEYKDRCMAD KTLPECSKLPNNVLQEKICA MEGLPQKHNFSHCCSKVDAQ RRLCFFYNKKSDVGFLPPFP TLDPEEKCQAYESNRESLLN HFLYEVARRNPFVFAPTLLT VAVHFEEVAKSCCEEQNKVN CLQTRAIPVTQYLKAFSSYQ KHVCGALLKFGTKVVHFIY |
Additional Info
| Post Translational Modifications | N-glycosylated.more than 90% of the glycans are sialylated. |
| Function | Functions as a carrier for hydrophobic molecules in body fluids (Probable). Essential for the solubility and activity of lipidated Wnt family members, including WNT1, WNT2B, WNT3, WNT3A, WNT5A, WNT7A, WNT7B, WNT8, WNT9A, WNT9B, WNT10A and WNT10B. Binds vitamin E. May transport vitamin E in body fluids under conditions where the lipoprotein system is not sufficient. May be involved in the transport of vitamin E across the blood-brain barrier. |
| Protein Name | AfaminAlpha-AlbuminAlpha-Alb |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Afamin proteinAlpha-Albumin proteinAlpha-Alb proteinAFM proteinALB2 proteinALBA protein |
Information sourced from Uniprot.org