| Host: |
HEK293 cells |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: |
Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: |
<0.1 EU/Mu g |
| Gene Symbol: |
AFM |
| Gene ID: |
173 |
| Uniprot ID: |
AFAM_HUMAN |
| Immunogen Region: |
Met1-Asn599 |
| Immunogen: |
Recombinant Human Afamin/AFM Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Asn599) of human Afamin/AFM (Accession #NP_001124.1) fused with and a 6×His tag at the C-terminus. |
| Immunogen Sequence: |
MKLLKLTGFIFFLFFLTESL TLPTQPRDIENFNSTQKFIE DNIEYITIIAFAQYVQEATF EEMEKLVKDMVEYKDRCMAD KTLPECSKLPNNVLQEKICA MEGLPQKHNFSHCCSKVDAQ RRLCFFYNKKSDVGFLPPFP TLDPEEKCQAYESNRESLLN HFLYEVARRNPFVFAPTLLT VAVHFEEVAKSCCEEQNKVN CLQTRAIPVTQYLKAFSSYQ KHVCGALLKFGTKVVHFIY |
| Post Translational Modifications | N-glycosylated.more than 90% of the glycans are sialylated. |
| Function | Functions as a carrier for hydrophobic molecules in body fluids (Probable). Essential for the solubility and activity of lipidated Wnt family members, including WNT1, WNT2B, WNT3, WNT3A, WNT5A, WNT7A, WNT7B, WNT8, WNT9A, WNT9B, WNT10A and WNT10B. Binds vitamin E. May transport vitamin E in body fluids under conditions where the lipoprotein system is not sufficient. May be involved in the transport of vitamin E across the blood-brain barrier. |
| Protein Name | AfaminAlpha-AlbuminAlpha-Alb |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Afamin proteinAlpha-Albumin proteinAlpha-Alb proteinAFM proteinALB2 proteinALBA protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
