| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human ADSL-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | ADSL |
| Gene ID: | 158 |
| Uniprot ID: | PUR8_HUMAN |
| Immunogen Region: | Ala146-Leu484 |
| Immunogen: | Homo sapiens (Human) |
| Function | Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate. |
| Protein Name | Adenylosuccinate LyaseAdslAslAdenylosuccinaseAsase |
| Database Links | Reactome: R-HSA-73817 |
| Alternative Protein Names | Adenylosuccinate Lyase proteinAdsl proteinAsl proteinAdenylosuccinase proteinAsase proteinADSL proteinAMPS protein |
Information sourced from Uniprot.org