Tissue Specificity | |
Post Translational Modifications | Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase. |
Function | Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling. Involved in the regulation of sleep/wake behaviors. |
Protein Name | Beta-1 Adrenergic ReceptorBeta-1 AdrenoreceptorBeta-1 Adrenoceptor |
Database Links | Reactome: R-HSA-390696Reactome: R-HSA-418555 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinEarly EndosomeColocalizes With Rapgef2 At The Plasma MembraneLocalized At The Plasma MembraneFound In The Golgi Upon Gopc Overexpression |
Alternative ELISA Names | Beta-1 Adrenergic Receptor ELISA kitBeta-1 Adrenoreceptor ELISA kitBeta-1 Adrenoceptor ELISA kitADRB1 ELISA kitADRB1R ELISA kitB1AR ELISA kit |
output | |
Information sourced from Uniprot.org