This human ADIPOR1 kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes in serum, plasma and other biological fluids.
Applications
CLIA
Reactivity
Human
Sensitivity
0.09ng/mL
Detection Limit
0.16~10ng/mL
Note
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Product Properties
Storage Instruction
If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual.
This kit recognizes Human ADIPOR1 in samples. No significant cross-reactivity or interference between Human ADIPOR1 and analogues was observed.
Sample Type
Serum, plasma and other biological fluids
Additional Info
Tissue Specificity
Widely expressed. Highly expressed in heart and skeletal muscle. Expressed at intermediate level in brain, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes. Weakly expressed in colon, thymus and small intestine.
Function
Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism. Required for normal glucose and fat homeostasis and for maintaining a normal body weight. ADIPOQ-binding activates a signaling cascade that leads to increased AMPK activity, and ultimately to increased fatty acid oxidation, increased glucose uptake and decreased gluconeogenesis. Has high affinity for globular adiponectin and low affinity for full-length adiponectin.
Protein Name
Adiponectin Receptor Protein 1Progestin And Adipoq Receptor Family Member 1Progestin And Adipoq Receptor Family Member I
Cell MembraneMulti-Pass Membrane ProteinLocalized To The Cell Membrane And Intracellular Organelles
Alternative CLIA Names
Adiponectin Receptor Protein 1 CLIA kitProgestin And Adipoq Receptor Family Member 1 CLIA kitProgestin And Adipoq Receptor Family Member I CLIA kitADIPOR1 CLIA kitPAQR1 CLIA kitTESBP1A CLIA kitCGI-45 CLIA kit
Specificity
This kit recognizes Human ADIPOR1 in samples. No significant cross-reactivity or interference between Human ADIPOR1 and analogues was observed.