| Short Description : | Recombinant-Human ADGRB3-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications: | ELISA/WB |
| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Formulation: | Lyophilized from a 0.22 Mu m filtered solution in 20mM PB, 150mM NaCl, 5% Thehalose, pH 7.2. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | < 1 EU/µg as determined by LAL test. |
| Gene Symbol: | ADGRB3 |
| Gene ID: | 577 |
| Uniprot ID: | AGRB3_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Ala25-Thr880 |
| Post Translational Modifications | The endogenous protein is proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit. |
| Function | Receptor that plays a role in the regulation of synaptogenesis and dendritic spine formation at least partly via interaction with ELMO1 and RAC1 activity. Promotes myoblast fusion through ELMO/DOCK1. |
| Protein Name | Adhesion G Protein-Coupled Receptor B3Brain-Specific Angiogenesis Inhibitor 3 |
| Database Links | |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Protein Names | Adhesion G Protein-Coupled Receptor B3 proteinBrain-Specific Angiogenesis Inhibitor 3 proteinADGRB3 proteinBAI3 proteinKIAA0550 protein |
Information sourced from Uniprot.org