Human Adenylate cyclase type 10/ADCY10 protein (Recombinant) (N-His) (STJP015125)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human Adenylate cyclase type 10/ADCY10-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-174°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | ADCY10 |
| Gene ID | 55811 |
| Uniprot ID | ADCYA_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Gln461 |
Additional Info
| Post Translational Modifications | Cleavage may occur to generate the active 48 kDa form. |
| Function | Catalyzes the formation of the signaling molecule cAMP. May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels. Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. Involved in ciliary beat regulation. |
| Protein Name | Adenylate Cyclase Type 10Ah-Related ProteinAdenylate Cyclase HomologGerm Cell Soluble Adenylyl CyclaseHsacSacTesticular Soluble Adenylyl Cyclase |
| Database Links | Reactome: R-HSA-5610787 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmCytoskeletonPerinuclear RegionNucleusCell ProjectionCiliumMitochondrionDistributed To Subcellular Compartments Containing Camp TargetsFound As A Plasma Membrane-Associated ProteinProtein Concentrated In The Perinuclear Region And Protein Colocalized With Actin Or Tubulin |
| Alternative Protein Names | Adenylate Cyclase Type 10 proteinAh-Related Protein proteinAdenylate Cyclase Homolog proteinGerm Cell Soluble Adenylyl Cyclase proteinHsac proteinSac proteinTesticular Soluble Adenylyl Cyclase proteinADCY10 proteinSAC protein |
Information sourced from Uniprot.org