Human Adenylate cyclase type 10/ADCY10 protein (Recombinant) (N-His) (STJP015125)

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STJP015125
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Host: E.coli
Applications: ELISA/Immunogen/SDS-PAGE/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human Adenylate cyclase type 10/ADCY10-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Dilution Range: 0
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-174°C for twelve months from the date of receipt.
Endotoxin: Please contact us for further information.
Gene Symbol: ADCY10
Gene ID: 55811
Uniprot ID: ADCYA_HUMAN
Immunogen Region: Met1-Gln461
Immunogen: Homo sapiens (Human)
Post Translational Modifications Cleavage may occur to generate the active 48 kDa form.
Function Catalyzes the formation of the signaling molecule cAMP. May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels. Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. Involved in ciliary beat regulation.
Protein Name Adenylate Cyclase Type 10
Ah-Related Protein
Adenylate Cyclase Homolog
Germ Cell Soluble Adenylyl Cyclase
Hsac
Sac
Testicular Soluble Adenylyl Cyclase
Database Links Reactome: R-HSA-5610787
Cellular Localisation Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Cytoplasm
Cytoskeleton
Perinuclear Region
Nucleus
Cell Projection
Cilium
Mitochondrion
Distributed To Subcellular Compartments Containing Camp Targets
Found As A Plasma Membrane-Associated Protein
Protein Concentrated In The Perinuclear Region And Protein Colocalized With Actin Or Tubulin
Alternative Protein Names Adenylate Cyclase Type 10 protein
Ah-Related Protein protein
Adenylate Cyclase Homolog protein
Germ Cell Soluble Adenylyl Cyclase protein
Hsac protein
Sac protein
Testicular Soluble Adenylyl Cyclase protein
ADCY10 protein
SAC protein

Information sourced from Uniprot.org

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