Human ADCYAP1 (Adenylate Cyclase Activating Polypeptide 1, Pituitary) Sandwich ELISA Kit (STJE0006915)

SKU:
STJE0006915
£404.50 - £562.50
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 2.3pg/mL
Detection Limit: 7.81-500pg/mL
Short Description : This ADCYAP1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids..
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: ADCYAP1
Gene ID: 116
Uniprot ID: PACA_HUMAN
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity
Post Translational Modifications
Function PACAP is a neuropeptide involved in diverse array of physiological processes through activating the PACAP subfamily of class B1 G protein-coupled receptors: VIP receptor 1 (VIPR1), VIP receptor 2 (VIPR2), and PACAP type I receptor (ADCYAP1R1). Exerts neuroprotective and general cytoprotective effects due to anti-apoptotic, anti-inflammatory, and antioxidant actions. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion. Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells. PACAP exists in two bioactive forms from proteolysis of the same precursor protein, PACAP27 and PACAP38, which differ by eleven amino acid residues in the C-terminus.
Protein Name Pituitary Adenylate Cyclase-Activating Polypeptide
Pacap Cleaved Into - Pacap-Related Peptide
Prp-48 - Pituitary Adenylate Cyclase-Activating Polypeptide 27
Pacap-27
Pacap27 - Pituitary Adenylate Cyclase-Activating Polypeptide 38
Pacap-38
Pacap38
Database Links Reactome: R-HSA-187024
Reactome: R-HSA-418555
Reactome: R-HSA-420092
Cellular Localisation Secreted
Alternative ELISA Names Pituitary Adenylate Cyclase-Activating Polypeptide ELISA kit
Pacap Cleaved Into - Pacap-Related Peptide ELISA kit
Prp-48 - Pituitary Adenylate Cyclase-Activating Polypeptide 27 ELISA kit
Pacap-27 ELISA kit
Pacap27 - Pituitary Adenylate Cyclase-Activating Polypeptide 38 ELISA kit
Pacap-38 ELISA kit
Pacap38 ELISA kit
ADCYAP1 ELISA kit
output

Information sourced from Uniprot.org