| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.28ng/mL |
| Detection Limit: | 0.781-50ng/mL |
| Short Description : | This ADCY1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 4.5 hrs |
| Gene Symbol: | ADCY1 |
| Gene ID: | 107 |
| Uniprot ID: | ADCY1_HUMAN |
| Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | Detected in zona glomerulosa and zona fasciculata in the adrenal gland (at protein level). Brain, retina and adrenal medulla. |
| Post Translational Modifications | N-glycosylated. |
| Function | Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates responses to increased cellular Ca(2+)/calmodulin levels. May be involved in regulatory processes in the central nervous system. May play a role in memory and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina. |
| Protein Name | Adenylate Cyclase Type 1 Atp Pyrophosphate-Lyase 1 Adenylate Cyclase Type I Adenylyl Cyclase 1 Ca(2+/Calmodulin-Activated Adenylyl Cyclase |
| Database Links | Reactome: R-HSA-163359 Reactome: R-HSA-163615 Reactome: R-HSA-164378 Reactome: R-HSA-170660 Reactome: R-HSA-170670 Reactome: R-HSA-418555 Reactome: R-HSA-418594 Reactome: R-HSA-418597 Reactome: R-HSA-432040 Reactome: R-HSA-442720 Reactome: R-HSA-5610787 Reactome: R-HSA-9634597 Reactome: R-HSA-9660821 Reactome: R-HSA-9664323 |
| Cellular Localisation | Membrane Multi-Pass Membrane Protein Cell Membrane Cytoplasm Membrane Raft Expressed In The Cytoplasm Of Supporting Cells And Hair Cells Of The Cochlea Vestibule As Well As To The Cochlear Hair Cell Nuclei And Stereocilia |
| Alternative ELISA Names | Adenylate Cyclase Type 1 ELISA kit Atp Pyrophosphate-Lyase 1 ELISA kit Adenylate Cyclase Type I ELISA kit Adenylyl Cyclase 1 ELISA kit Ca(2+/Calmodulin-Activated Adenylyl Cyclase ELISA kit ADCY1 ELISA kit |
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Information sourced from Uniprot.org