| Host: | HEK293 |
| Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human ADAM8-protein was developed from hek293. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
| Dilution Range: | Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
| Storage Instruction: | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
| Gene Symbol: | ADAM8 |
| Gene ID: | 101 |
| Uniprot ID: | ADAM8_HUMAN |
| Immunogen Region: | ILE17-LEU665 |
| Immunogen: | Optimized DNA sequence encoding extracellular domain of human Disintegrin and metalloproteinase 8 (ILE17-LEU665) including a C-terminal His tag was expressed in HEK293 cells. NA |
| Tissue Specificity | Expressed on neutrophils and monocytes. |
| Function | Possible involvement in extravasation of leukocytes. |
| Protein Name | Disintegrin And Metalloproteinase Domain-Containing Protein 8Adam 8Cell Surface Antigen Ms2Cd Antigen Cd156a |
| Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-6798695 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Disintegrin And Metalloproteinase Domain-Containing Protein 8 proteinAdam 8 proteinCell Surface Antigen Ms2 proteinCd Antigen Cd156a proteinADAM8 proteinMS2 protein |
Information sourced from Uniprot.org
