| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of 50mM Tris, 10mM CaCl2, 150mM NaCl, pH 7.5. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 1.0 EU/Mu g of the protein by LAL method. |
| Immunoreactivity: | Measured by its ability to cleave a fluorogenic peptide substrate Mca-PLAQAV-Dpa-RSSSR-NH2.The specific activity is >2 pmol/min/Mu g. |
| Gene Symbol: | ADAM8 |
| Gene ID: | 101 |
| Uniprot ID: | ADAM8_HUMAN |
| Immunogen: | Recombinant Human ADAM8/CD156a Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Pro497) of human ADAM8/CD156a (Accession #NP_001100.3) fused with a 6×His tag at the C-terminus. |
| Immunogen Sequence: | MRGLGLWLLGAMMLPAIAPS RPWALMEQYEVVLPWRLPGP RVRRALPSHLGLHPERVSYV LGATGHNFTLHLRKNRDLLG SGYTETYTAANGSEVTEQPR GQDHCFYQGHVEGYPDSAAS LSTCAGLRGFFQVGSDLHLI EPLDEGGEGGRHAVYQAEHL LQTAGTCGVSDDSLGSLLGP RTAAVFRPRPGDSLPSRETR YVELYVVVDNAEFQMLGSEA AVRHRVLEVVNHVDKLYQK |
| Function | Possible involvement in extravasation of leukocytes. |
| Protein Name | Disintegrin And Metalloproteinase Domain-Containing Protein 8Adam 8Cell Surface Antigen Ms2Cd Antigen Cd156a |
| Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-6798695 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Disintegrin And Metalloproteinase Domain-Containing Protein 8 proteinAdam 8 proteinCell Surface Antigen Ms2 proteinCd Antigen Cd156a proteinADAM8 proteinMS2 protein |
Information sourced from Uniprot.org