Human ADAM22 protein (Recombinant) (N-His) (STJP006116)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human ADAM22-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | ADAM22 |
| Gene ID | 53616 |
| Uniprot ID | ADA22_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Leu370-Asn582 |
Additional Info
| Post Translational Modifications | The precursor is cleaved by a furin endopeptidase. |
| Function | Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein. Involved in regulation of cell adhesion and spreading and in inhibition of cell proliferation. Neuronal receptor for LGI1. |
| Protein Name | Disintegrin And Metalloproteinase Domain-Containing Protein 22Adam 22Metalloproteinase-Disintegrin Adam22-3Metalloproteinase-Like - Disintegrin-Like - And Cysteine-Rich Protein 2 |
| Database Links | Reactome: R-HSA-5682910 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell ProjectionAxon |
| Alternative Protein Names | Disintegrin And Metalloproteinase Domain-Containing Protein 22 proteinAdam 22 proteinMetalloproteinase-Disintegrin Adam22-3 proteinMetalloproteinase-Like - Disintegrin-Like - And Cysteine-Rich Protein 2 proteinADAM22 proteinMDC2 protein |
Information sourced from Uniprot.org