Human ADAM22 protein (Recombinant) (N-His) (STJP006116)

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STJP006116
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ADAM22-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ADAM22
Gene ID: 53616
Uniprot ID: ADA22_HUMAN
Immunogen Region: Leu370-Asn582
Immunogen: Homo sapiens (Human)
Post Translational Modifications The precursor is cleaved by a furin endopeptidase.
Function Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein. Involved in regulation of cell adhesion and spreading and in inhibition of cell proliferation. Neuronal receptor for LGI1.
Protein Name Disintegrin And Metalloproteinase Domain-Containing Protein 22
Adam 22
Metalloproteinase-Disintegrin Adam22-3
Metalloproteinase-Like - Disintegrin-Like - And Cysteine-Rich Protein 2
Database Links Reactome: R-HSA-5682910
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Projection
Axon
Alternative Protein Names Disintegrin And Metalloproteinase Domain-Containing Protein 22 protein
Adam 22 protein
Metalloproteinase-Disintegrin Adam22-3 protein
Metalloproteinase-Like - Disintegrin-Like - And Cysteine-Rich Protein 2 protein
ADAM22 protein
MDC2 protein

Information sourced from Uniprot.org

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