Human ADAM12 protein (Recombinant) (N-His) (STJP003258)

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STJP003258
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ADAM12-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ADAM12
Gene ID: 8038
Uniprot ID: ADA12_HUMAN
Immunogen Region: Val31-His350
Immunogen: Homo sapiens (Human)
Post Translational Modifications The precursor is cleaved by a furin endopeptidase.
Function Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors.
Protein Name Disintegrin And Metalloproteinase Domain-Containing Protein 12
Adam 12
Meltrin-Alpha
Database Links Reactome: R-HSA-177929
Reactome: R-HSA-8941237
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Secreted
Isoform 3: Secreted
Isoform 4: Secreted
Alternative Protein Names Disintegrin And Metalloproteinase Domain-Containing Protein 12 protein
Adam 12 protein
Meltrin-Alpha protein
ADAM12 protein
MLTN protein
UNQ346 protein
PRO545 protein

Information sourced from Uniprot.org

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