| Host: |
CHO cells |
| Note: |
STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human Activin-protein was developed from cho cells. For use in research applications. |
| Conjugation: |
Unconjugated |
| Formulation: |
Lyophilised from 0.2 Mu m filtered solution in 0.2M AcOH, pH 4.0. |
| Dilution Range: |
Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
| Storage Instruction: |
Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin: |
Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
| Immunoreactivity: |
The ED (50) was determined by the dose-dependent proliferation ofmurine MCP11 cell line was found to be in the les than 1 ng/ml. NA |
| Gene Symbol: |
INHBA |
| Gene ID: |
3624 |
| Uniprot ID: |
INHBA_HUMAN |
| Immunogen: |
Optimized DNA sequence encoding Human Inhibin Beta Alpha Chain was expressed in Chinese Hamster Ovary cell line. NA |
| Immunogen Sequence: |
MPLLWLRGFL LASCWIIVRS SPTPGSEGHS AAPDCPSCAL AALPKDVPNS 50 QPEMVEAVKK HILNMLHLKK RPDVTQPVPK AALLNAIRKL HVGKVGENGY 100 VEIEDDIGRR AEMNELMEQT SEIITFAESG TARKTLHFEI SKEGSDLSVV 150 ERAEVWLFLK VPKANRTRTK VTIRLFQQQK HPQGSLDTGE EAEEVGLKGE 200 RSELLLSEKV VDAR |
| Function | Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. |
| Protein Name | Inhibin Beta A ChainActivin Beta-A ChainErythroid Differentiation ProteinEdf |
| Database Links | Reactome: R-HSA-1502540Reactome: R-HSA-209822Reactome: R-HSA-2473224 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Inhibin Beta A Chain proteinActivin Beta-A Chain proteinErythroid Differentiation Protein proteinEdf proteinINHBA protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
