Human ACSS1 protein (Recombinant) (N-His) (STJP006338)

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STJP006338
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ACSS1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ACSS1
Gene ID: 84532
Uniprot ID: ACS2L_HUMAN
Immunogen Region: Phe517-Lys689
Immunogen: Homo sapiens (Human)
Function Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Acetate is the preferred substrate. Can also utilize propionate with a much lower affinity. Provides acetyl-CoA that is utilized mainly for oxidation under ketogenic conditions. Involved in thermogenesis under ketogenic conditions, using acetate as a vital fuel when carbohydrate availability is insufficient.
Protein Name Acetyl-Coenzyme A Synthetase 2-Like - Mitochondrial
Acetate--Coa Ligase 2
Acetyl-Coa Synthetase 2
Acecs2
Acyl-Coa Synthetase Short-Chain Family Member 1
Propionate--Coa Ligase
Database Links Reactome: R-HSA-71384
Cellular Localisation Mitochondrion Matrix
Alternative Protein Names Acetyl-Coenzyme A Synthetase 2-Like - Mitochondrial protein
Acetate--Coa Ligase 2 protein
Acetyl-Coa Synthetase 2 protein
Acecs2 protein
Acyl-Coa Synthetase Short-Chain Family Member 1 protein
Propionate--Coa Ligase protein
ACSS1 protein
ACAS2L protein
KIAA1846 protein

Information sourced from Uniprot.org