| Short Description : | Recombinant-Human ACP2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE/Denatured |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 1 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ACP2 |
| Gene ID: | 53 |
| Uniprot ID: | PPAL_HUMAN |
| Accession Number: | NP_001601 |
| Immunogen: | Human |
| Immunogen Region: | 31-380aa |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MGSRSLRFVT LLYRHGDRSP VKTYPKDPYQ EEEWPQGFGQ LTKEGMLQHW ELGQALRQRY HGFLNTSYHR QEVYVRSTDF DRTLMSAEAN LAGLFPPNGM QRFNPNISWQ PIPVHTVPIT EDRLLKFPLG PCPRYEQLQN ETRQTPEYQN ESSRNAQFLD MVANETGLTD LTLETVWNVY DTLFCEQTHG LRLPPWASPQ TMQRLSRL |
| Post Translational Modifications | The membrane-bound form is converted to the soluble form by sequential proteolytic processing. First, the C-terminal cytoplasmic tail is removed. Cleavage by a lysosomal protease releases the soluble form in the lysosome lumen. N-glycosylated. The intermediates formed during enzymatic deglycosylation suggest that all eight predicted N-glycosylation sites are used. |
| Protein Name | Lysosomal Acid PhosphataseLap |
| Database Links | |
| Cellular Localisation | Lysosome MembraneSingle-Pass Membrane ProteinLumenal SideLysosome LumenThe Soluble Form Arises By Proteolytic Processing Of The Membrane-Bound Form |
| Alternative Protein Names | Lysosomal Acid Phosphatase proteinLap proteinACP2 protein |
Information sourced from Uniprot.org