Human ACADL protein (Recombinant) (N-His) (STJP004474)

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STJP004474
£328.50 - £1,437.50
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ACADL-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ACADL
Gene ID: 33
Uniprot ID: ACADL_HUMAN
Immunogen Region: Ile214-Lys430
Immunogen: Homo sapiens (Human)
Function Long-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, long-chain specific acyl-CoA dehydrogenase can act on saturated and unsaturated acyl-CoAs with 6 to 24 carbons with a preference for 8 to 18 carbons long primary chains.
Protein Name Long-Chain Specific Acyl-Coa Dehydrogenase - Mitochondrial
Lcad
Database Links Reactome: R-HSA-77285
Reactome: R-HSA-77288
Reactome: R-HSA-77310
Cellular Localisation Mitochondrion Matrix
Alternative Protein Names Long-Chain Specific Acyl-Coa Dehydrogenase - Mitochondrial protein
Lcad protein
ACADL protein

Information sourced from Uniprot.org