Human ABO protein (Recombinant-Active) (N-His) (STJP011890)

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STJP011890-100
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Short Description :Recombinant-Active-Human ABO-N-His protein was developed from mammalian cells and has a target region of N-His. For use in research applications.
Applications:ELISA/WB
Host:Mammalian Cells
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Unconjugated
Dilution Range:Reconstitute in sterile water for a stock solution.
Formulation:Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:<0.1 EU/Mu g of the protein by the LAL method.
Immunoreactivity:Measured by its ability to transfer galactose from UDPgalactose to lactoN-fucopentaose. The specific activity is >1, 250 pmol/min/Mu g, as measured under the described conditions.
Gene Symbol:ABO
Gene ID:28
Uniprot ID:BGAT_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Arg63-Pro354
Post Translational Modifications The soluble form derives from the membrane form by proteolytic processing.
Function This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. Glycosyltransferase that catalyzes the transfer of carbohydrates to H antigen, forming the antigenic structures of the ABO blood group.
Protein Name Histo-Blood Group Abo System Transferase
Fucosylglycoprotein 3-Alpha-Galactosyltransferase
Fucosylglycoprotein Alpha-N-Acetylgalactosaminyltransferase
Glycoprotein-Fucosylgalactoside Alpha-N-Acetylgalactosaminyltransferase
Glycoprotein-Fucosylgalactoside Alpha-Galactosyltransferase
Histo-Blood Group A Transferase
A Transferase
Histo-Blood Group B Transferase
B Transferase
Nagat Cleaved Into - Fucosylglycoprotein Alpha-N-Acetylgalactosaminyltransferase Soluble Form
Database Links Reactome: R-HSA-9033807
Cellular Localisation Golgi Apparatus
Golgi Stack Membrane
Single-Pass Type Ii Membrane Protein
Secreted
Membrane-Bound Form In Trans Cisternae Of Golgi
Secreted Into The Body Fluid
Alternative Protein Names Histo-Blood Group Abo System Transferase protein
Fucosylglycoprotein 3-Alpha-Galactosyltransferase protein
Fucosylglycoprotein Alpha-N-Acetylgalactosaminyltransferase protein
Glycoprotein-Fucosylgalactoside Alpha-N-Acetylgalactosaminyltransferase protein
Glycoprotein-Fucosylgalactoside Alpha-Galactosyltransferase protein
Histo-Blood Group A Transferase protein
A Transferase protein
Histo-Blood Group B Transferase protein
B Transferase protein
Nagat Cleaved Into - Fucosylglycoprotein Alpha-N-Acetylgalactosaminyltransferase Soluble Form protein
ABO protein

Information sourced from Uniprot.org

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