Human ABO protein (Recombinant-Active) (N-His) (STJP011890)

SKU:
STJP011890-100
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human ABO-N-His protein was developed from mammalian cells and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: ABO
Gene ID: 28
Uniprot ID: BGAT_HUMAN
Immunogen Region: Arg63-Pro354
Immunogen: Homo sapiens (Human)
Post Translational Modifications The soluble form derives from the membrane form by proteolytic processing.
Function This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. Glycosyltransferase that catalyzes the transfer of carbohydrates to H antigen, forming the antigenic structures of the ABO blood group.
Protein Name Histo-Blood Group Abo System Transferase
Fucosylglycoprotein 3-Alpha-Galactosyltransferase
Fucosylglycoprotein Alpha-N-Acetylgalactosaminyltransferase
Glycoprotein-Fucosylgalactoside Alpha-N-Acetylgalactosaminyltransferase
Glycoprotein-Fucosylgalactoside Alpha-Galactosyltransferase
Histo-Blood Group A Transferase
A Transferase
Histo-Blood Group B Transferase
B Transferase
Nagat Cleaved Into - Fucosylglycoprotein Alpha-N-Acetylgalactosaminyltransferase Soluble Form
Database Links Reactome: R-HSA-9033807
Cellular Localisation Golgi Apparatus
Golgi Stack Membrane
Single-Pass Type Ii Membrane Protein
Secreted
Membrane-Bound Form In Trans Cisternae Of Golgi
Secreted Into The Body Fluid
Alternative Protein Names Histo-Blood Group Abo System Transferase protein
Fucosylglycoprotein 3-Alpha-Galactosyltransferase protein
Fucosylglycoprotein Alpha-N-Acetylgalactosaminyltransferase protein
Glycoprotein-Fucosylgalactoside Alpha-N-Acetylgalactosaminyltransferase protein
Glycoprotein-Fucosylgalactoside Alpha-Galactosyltransferase protein
Histo-Blood Group A Transferase protein
A Transferase protein
Histo-Blood Group B Transferase protein
B Transferase protein
Nagat Cleaved Into - Fucosylglycoprotein Alpha-N-Acetylgalactosaminyltransferase Soluble Form protein
ABO protein

Information sourced from Uniprot.org