Name: Human ABHD2 protein (Recombinant) (N-His) (STJP008237)
SKU: STJP008237
Availability: InStock

Human ABHD2 protein (Recombinant) (N-His) (STJP008237)

SKU:

STJP008237

£328.50 - £1,437.50

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Host:	E. coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Recombinant-Human ABHD2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.

Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2AG, an inhibitor of the sperm calcium channel CatSper, leading to calcium influx via CatSper and sperm activation. May also play a role in smooth muscle cells migration.
Protein Name	Monoacylglycerol Lipase Abhd2 2-Arachidonoylglycerol Hydrolase Abhydrolase Domain-Containing Protein 2 Acetylesterase Lung Alpha/Beta Hydrolase 2 Progesterone-Sensitive Lipase Protein Phps1-2
Cellular Localisation	Cell Projection Cilium Flagellum Membrane Single-Pass Type Ii Membrane Protein Cell Membrane
Alternative Protein Names	Monoacylglycerol Lipase Abhd2 protein 2-Arachidonoylglycerol Hydrolase protein Abhydrolase Domain-Containing Protein 2 protein Acetylesterase protein Lung Alpha/Beta Hydrolase 2 protein Progesterone-Sensitive Lipase protein Protein Phps1-2 protein ABHD2 protein LABH2 protein

Information sourced from Uniprot.org

Model	Name	Host
STJP005172	Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172)	E. coli
STJP004723	Human WAS protein (Recombinant) (N-His) (STJP004723)	E. coli
STJP001380	Human TET2 protein (Recombinant) (N-his) (STJP001380)	HEK293 cells
STJP007831	Human TFE3 protein (Recombinant) (N-His) (STJP007831)	E. coli
STJP007833	Human SLC8A1 protein (Recombinant) (N-His) (STJP007833)	E. coli

Human ABHD2 protein (Recombinant) (N-His) (STJP008237)

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