Name: Human ABCD4 protein (Recombinant) (N-His) (STJP003191)
SKU: STJP003191
Availability: InStock

Human ABCD4 protein (Recombinant) (N-His) (STJP003191)

SKU:

STJP003191

$443.48 - $1,940.63

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Host:	E. coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Recombinant-Human ABCD4-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.

Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Lysosomal membrane protein that transports cobalamin (Vitamin B12) from the lysosomal lumen to the cytosol in an ATP-dependent manner. Targeted by LMBRD1 lysosomal chaperone from the endoplasmic reticulum to the lysosomal membrane. Then forms a complex with lysosomal chaperone LMBRD1 and cytosolic MMACHC to transport cobalamin across the lysosomal membrane.
Protein Name	Lysosomal Cobalamin Transporter Abcd4 Atp-Binding Cassette Sub-Family D Member 4 Pmp70-Related Protein P70r Peroxisomal Membrane Protein 1-Like Pxmp1-L Peroxisomal Membrane Protein 69 Pmp69
Database Links	Reactome: R-HSA-5683329 Reactome: R-HSA-9758881 Reactome: R-HSA-9758890
Cellular Localisation	Endoplasmic Reticulum Membrane Multi-Pass Membrane Protein Lysosome Membrane Targeted By Lmbrd1 Lysosomal Chaperone To The Lysosomal Membrane
Alternative Protein Names	Lysosomal Cobalamin Transporter Abcd4 protein Atp-Binding Cassette Sub-Family D Member 4 protein Pmp70-Related Protein protein P70r protein Peroxisomal Membrane Protein 1-Like protein Pxmp1-L protein Peroxisomal Membrane Protein 69 protein Pmp69 protein ABCD4 protein PXMP1L protein

Information sourced from Uniprot.org

Model	Name	Host
STJP005172	Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172)	E. coli
STJP004723	Human WAS protein (Recombinant) (N-His) (STJP004723)	E. coli
STJP008089	Human SNX1 protein (Recombinant) (N-His) (STJP008089)	E. coli
STJP008092	Human TBX5 protein (Recombinant) (N-His) (STJP008092)	E. coli
STJP008101	Human ARL2BP protein (Recombinant) (N-His) (STJP008101)	E. coli

Human ABCD4 protein (Recombinant) (N-His) (STJP003191)

General Information