Human ABCD3 protein (Recombinant) (N-His) (STJP004467)

SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
STJP004467
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General Information

Short DescriptionRecombinant-Human ABCD3-N-His protein was developed from e.coli for the region N-His. For use in research applications.
ApplicationsELISA/Immunogen/SDS-PAGE/WB
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Dilution RangeReconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
FormulationLyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Target Information

Gene SymbolABCD3
Gene ID5825
Uniprot IDABCD3_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionPro425-Ser659

Additional Info

Function Broad substrate specificity ATP-dependent transporter of the ATP-binding cassette (ABC) family that catalyzes the transport of long-chain fatty acids (LCFA)-CoA, dicarboxylic acids-CoA, long-branched-chain fatty acids-CoA and bile acids from the cytosol to the peroxisome lumen for beta-oxydation. Has fatty acyl-CoA thioesterase and ATPase activities. Probably hydrolyzes fatty acyl-CoAs into free fatty acids prior to their ATP-dependent transport into peroxisomes. Thus, play a role in regulation of LCFAs and energy metabolism namely, in the degradation and biosynthesis of fatty acids by beta-oxidation.
Protein Name Atp-Binding Cassette Sub-Family D Member 3
70 Kda Peroxisomal Membrane Protein
Pmp70
Database Links Reactome: R-HSA-1369062
Reactome: R-HSA-8980692
Reactome: R-HSA-9013106
Reactome: R-HSA-9603798
Cellular Localisation Peroxisome Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Atp-Binding Cassette Sub-Family D Member 3 protein
70 Kda Peroxisomal Membrane Protein protein
Pmp70 protein
ABCD3 protein
PMP70 protein
PXMP1 protein

Information sourced from Uniprot.org

Citations

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