| Function | ATP-dependent low-affinity peptide transporter which translocates a broad spectrum of peptides from the cytosol to the lysosomal lumen for degradation. Displays a broad peptide length specificity from 6-mer up to at least 59-mer peptides with an optimum of 23-mers. Binds and transports smaller and larger peptides with the same affinity. Favors positively charged, aromatic or hydrophobic residues in the N- and C-terminal positions whereas negatively charged residues as well as asparagine and methionine are not favored. |
| Protein Name | Abc-Type Oligopeptide Transporter Abcb9Atp-Binding Cassette Sub-Family B Member 9Atp-Binding Cassette Transporter 9Abc Transporter 9 ProteinHabcb9Tap-Like ProteinTapl |
| Database Links | Reactome: R-HSA-382556 |
| Cellular Localisation | Lysosome MembraneMulti-Pass Membrane ProteinMay Be Located In Membrane RaftsTakes An Intracellular Route From The Endoplasmic Reticulum (Er)Via Golgi And Early Endosomes To Late Endosomal And Lysosomal Compartments |
| Alternative Protein Names | Abc-Type Oligopeptide Transporter Abcb9 proteinAtp-Binding Cassette Sub-Family B Member 9 proteinAtp-Binding Cassette Transporter 9 proteinAbc Transporter 9 Protein proteinHabcb9 proteinTap-Like Protein proteinTapl proteinABCB9 proteinKIAA1520 protein |
Information sourced from Uniprot.org
