Tissue Specificity | Highly expressed in pineal gland and at lower levels in the retina. Weak expression in several brain regions and in the pituitary gland. |
Post Translational Modifications | cAMP-dependent phosphorylation on both N-terminal Thr-31 and C-terminal Ser-205 regulates AANAT activity by promoting interaction with 14-3-3 proteins. |
Function | Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin. |
Protein Name | Serotonin N-AcetyltransferaseSerotonin AcetylaseAralkylamine N-AcetyltransferaseAa-Nat |
Database Links | Reactome: R-HSA-209931 |
Cellular Localisation | Cytoplasm |
Alternative ELISA Names | Serotonin N-Acetyltransferase ELISA kitSerotonin Acetylase ELISA kitAralkylamine N-Acetyltransferase ELISA kitAa-Nat ELISA kitAANAT ELISA kitSNAT ELISA kit |
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Information sourced from Uniprot.org