Human 4-1BB (CD137) protein (Recombinant) (STJP000593)

Name: Human 4-1BB (CD137) protein (Recombinant) (STJP000593)
SKU: STJP000593
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostCHO Cells

ConjugationUnconjugated

ImmunogenOptimized DNA sequence encoding Human 4-1BB (CD137) fused to a C terminal IgG1 Fc tag was expressed in CHO Cells. NA

STJP000593

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Short Description	Recombinant-Human 4-1BB (CD137)-protein was developed from cho cells. For use in research applications.
Host	CHO Cells
Note	STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation	Unconjugated
Formulation	Lyophilised 0.2 Mu m filtered PBS solution, pH7.2.
Storage Instruction	Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA
Endotoxin	Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA
Immunoreactivity	The activity was tested by the ability of immobilized recombinant mouse 4-1BBL to bind human 4-1BB with a linear range of 10-500 ng/ml NA

Gene Symbol	TNFRSF9
Gene ID	3604
Uniprot ID	TNR9_HUMAN
Immunogen	Optimized DNA sequence encoding Human 4-1BB (CD137) fused to a C terminal IgG1 Fc tag was expressed in CHO Cells. NA
Immunogen Region	C-Term

Tissue Specificity	Expressed on the surface of activated T-cells.
Function	Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable).
Protein Name	Tumor Necrosis Factor Receptor Superfamily Member 9 4-1bb Ligand Receptor Cdw137 T-Cell Antigen 4-1bb Homolog T-Cell Antigen Ila Cd Antigen Cd137
Database Links	Reactome: R-HSA-5669034
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	Tumor Necrosis Factor Receptor Superfamily Member 9 protein 4-1bb Ligand Receptor protein Cdw137 protein T-Cell Antigen 4-1bb Homolog protein T-Cell Antigen Ila protein Cd Antigen Cd137 protein TNFRSF9 protein CD137 protein ILA protein

Information sourced from Uniprot.org