| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
GLUT9 Blocking Peptide is synthetically produced from the 50-570 sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
SLC2A9 |
| Gene ID: |
56606 |
| Uniprot ID: |
GTR9_HUMAN |
| Immunogen Region: |
50-570 |
| Immunogen: |
Synthetic peptide taken within amino acid region 50-570 on Glut 9 protein. |
| Tissue Specificity | Isoform 1: Most strongly expressed in basolateral membranes of proximal renal tubular cells, liver and placenta. Also detected in lung, blood leukocytes, heart skeletal muscle and chondrocytes from articular cartilage. Detected in kidney membrane (at protein level). Isoform 2: Only detected in the apical membranes of polarized renal tubular cells and placenta. Detected in kidney membrane (at protein level). |
| Function | High-capacity urate transporter, which may play a role in the urate reabsorption by proximal tubules. May have a residual high-affinity, low-capacity glucose and fructose transporter activity. Transports urate at rates 45- to 60-fold faster than glucose. Does not transport galactose. May mediate small uptake of adenine but not of other nucleobases. |
| Peptide Name | Solute Carrier Family 2 - Facilitated Glucose Transporter Member 9Glucose Transporter Type 9Glut-9Urate Transporter |
| Database Links | Reactome: R-HSA-189200Reactome: R-HSA-5619047 |
| Cellular Localisation | Isoform 1: Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell MembraneIsoform 2: Cell MembraneApical Cell Membrane |
| Alternative Peptide Names | Solute Carrier Family 2 - Facilitated Glucose Transporter Member 9 proteinGlucose Transporter Type 9 proteinGlut-9 proteinUrate Transporter proteinSLC2A9 proteinGLUT9 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
