| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Glucose-6-Phosphate, catalytic subunit Blocking Peptide for STJ501115 is synthetically produced from the 80-130 sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
G6pc2 |
| Gene ID: |
14378 |
| Uniprot ID: |
G6PC2_MOUSE |
| Immunogen Region: |
80-130 |
| Specificity: |
This blocking peptide is recommended for use in combination with Glucose-6-Phosphate, catalytic subunit antibody, STJ501115 |
| Immunogen: |
Synthetic peptide taken within amino acid region 80-130 on G6PC2 protein, and common in larger variant of glucose 6 phosphatase. |
| Tissue Specificity | Specifically expressed in pancreatic islet cells, in particular those of beta-cell origin. Not detected in testis, kidney, muscle, liver, lung, spleen, brain, pituitary, gastric fundus or heart. |
| Post Translational Modifications | N-glycosylated.the non-glycosylated form is more unstable and is degraded through the proteasome. |
| Function | May hydrolyze glucose-6-phosphate to glucose in the endoplasmic reticulum. May be responsible for glucose production through glycogenolysis and gluconeogenesis. |
| Peptide Name | Glucose-6-Phosphatase 2G-6-Pase 2G6pase 2Islet-Specific Glucose-6-Phosphatase Catalytic Subunit-Related Protein |
| Database Links | Reactome: R-MMU-70263 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | Glucose-6-Phosphatase 2 proteinG-6-Pase 2 proteinG6pase 2 proteinIslet-Specific Glucose-6-Phosphatase Catalytic Subunit-Related Protein proteinG6pc2 proteinIgrp protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
