| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
GIRK1 Blocking Peptide for STJ501164 is synthetically produced from the 420-470 sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
Kcnj3 |
| Gene ID: |
50599 |
| Uniprot ID: |
KCNJ3_RAT |
| Immunogen Region: |
420-470 |
| Specificity: |
This blocking peptide is recommended for use in combination with GIRK1 antibody, STJ501164 |
| Immunogen: |
Synthetic peptide taken within amino acid region 420-470 rat GIRK1 protein. |
| Function | This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium.as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat. |
| Peptide Name | G Protein-Activated Inward Rectifier Potassium Channel 1Girk-1Inward Rectifier K(+ Channel Kir3.1KgaKgb1Potassium Channel - Inwardly Rectifying Subfamily J Member 3 |
| Database Links | Reactome: R-RNO-1296041Reactome: -RNO-997272 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | G Protein-Activated Inward Rectifier Potassium Channel 1 proteinGirk-1 proteinInward Rectifier K(+ Channel Kir3.1 proteinKga proteinKgb1 proteinPotassium Channel - Inwardly Rectifying Subfamily J Member 3 proteinKcnj3 proteinGirk1 proteinKga protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
