FNDC5 Positive Control for STJ501505 peptide (STJ504325)

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STJ504325-5

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Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: FNDC5 Positive Control for STJ501505 is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range: WB: 1:500
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Fndc5
Gene ID: 384061
Uniprot ID: FNDC5_MOUSE
Specificity: This is positive control is recommended for use in combination with FNDC5 antibody STJ501505.
Tissue Specificity In adult, it is highly expressed in skeletal muscle, heart and brain.
Post Translational Modifications The extracellular domain is cleaved and released from the cell membrane. N-Glycosylated.
Function Irisin: Mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA.
Peptide Name Fibronectin Type Iii Domain-Containing Protein 5
Fibronectin Type Iii Repeat-Containing Protein 2
Peroxisomal Protein
Pep Cleaved Into - Irisin
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Peroxisome Membrane
Secreted
Imported In Peroxisomes Through The Pex5 Receptor Pathway
Irisin: Secreted
Detected In The Blood Of Individuals Subjected To Endurance Exercise
Alternative Peptide Names Fibronectin Type Iii Domain-Containing Protein 5 protein
Fibronectin Type Iii Repeat-Containing Protein 2 protein
Peroxisomal Protein protein
Pep Cleaved Into - Irisin protein
Fndc5 protein
Frcp2 protein
Pep protein

Information sourced from Uniprot.org

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