ELOVL4 Blocking Peptide is synthetically produced from the 1-100 sequence and is suitable for use in western blot applications.
Applications
Immunodepletion/Immunocompetition
Note
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Product Properties
Formulation
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction
Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles.
Synthetic peptide taken within amino acid region 1-100 on ELOV4 human protein.
Immunogen Region
1-100
Additional Info
Tissue Specificity
Expressed in the retina and at much lower level in the brain. Ubiquitous, highest expression in thymus, followed by testis, small intestine, ovary, and prostate. Little or no expression in heart, lung, liver, or leukocates.
Post Translational Modifications
N-glycosylated.
Function
Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that catalyzes the synthesis of very long chain saturated (VLC-SFA) and polyunsaturated (PUFA) fatty acids that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May play a critical role in early brain and skin development.
Peptide Name
Very Long Chain Fatty Acid Elongase 43-Keto Acyl-Coa Synthase Elovl4Elovl Fatty Acid Elongase 4Elovl Fa Elongase 4Elongation Of Very Long Chain Fatty Acids Protein 4Very Long Chain 3-Ketoacyl-Coa Synthase 4Very Long Chain 3-Oxoacyl-Coa Synthase 4
Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein
Alternative Peptide Names
Very Long Chain Fatty Acid Elongase 4 protein3-Keto Acyl-Coa Synthase Elovl4 proteinElovl Fatty Acid Elongase 4 proteinElovl Fa Elongase 4 proteinElongation Of Very Long Chain Fatty Acids Protein 4 proteinVery Long Chain 3-Ketoacyl-Coa Synthase 4 proteinVery Long Chain 3-Oxoacyl-Coa Synthase 4 proteinELOVL4 protein
