| Applications: |
Immunodepletion/Immunocompetition |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Dystrophin Blocking Peptide for STJ507807 is synthetically produced from the 200-250 sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
DMD |
| Gene ID: |
1756 |
| Uniprot ID: |
DMD_HUMAN |
| Immunogen Region: |
200-250 |
| Specificity: |
This blocking peptide is recommended for use in combination with Dystrophin antibody, STJ507807 |
| Immunogen: |
Synthetic peptide corresponding to amino acids within region 200-250 on rat 5-hydroxytrptamine receptor 1A protein. |
| Function | Anchors the extracellular matrix to the cytoskeleton via F-actin. Ligand for dystroglycan. Component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma. Also implicated in signaling events and synaptic transmission. |
| Peptide Name | Dystrophin |
| Database Links | Reactome: R-HSA-3000171Reactome: R-HSA-390522 |
| Cellular Localisation | Cell MembraneSarcolemmaPeripheral Membrane ProteinCytoplasmic SideCytoplasmCytoskeletonPostsynaptic Cell MembraneIn Muscle CellsSarcolemma Localization Requires The Presence Of Ank2While Localization To Costameres Requires The Presence Of Ank3Localizes To Neuromuscular Junctions (Nmjs)In Adult MuscleNmj Localization Depends Upon Ank2 PresenceBut Not In Newborn Animals |
| Alternative Peptide Names | Dystrophin proteinDMD protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
