Dopamine Transporter Blocking Peptide peptide (STJ503947)

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STJ503947-250
$380.03
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Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Dopamine Transporter Blocking Peptide is synthetically produced from the 550-600 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: SLC6A3
Gene ID: 6531
Uniprot ID: SC6A3_HUMAN
Immunogen Region: 550-600
Immunogen: Synthetic peptide taken within amino acid region 550-600 on SLC6A3 protein.
Tissue Specificity Highly expressed in substantia nigra. Expressed in axonal varicosities in dopaminergic nerve terminals (at protein level). Expressed in the striatum (at protein level).
Function Mediates sodium- and chloride-dependent transport of dopamine. Also mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline). Regulator of light-dependent retinal hyaloid vessel regression, downstream of OPN5 signaling.
Peptide Name Sodium-Dependent Dopamine Transporter
Da Transporter
Dat
Solute Carrier Family 6 Member 3
Database Links Reactome: R-HSA-379401
Reactome: R-HSA-442660
Reactome: R-HSA-5619081
Reactome: R-HSA-5660724
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cell Projection
Neuron Projection
Axon
Localizes To Neurite Tips In Neuronal Cells
Colocalizes With Septin4 At Axon Terminals
Especially At The Varicosities
Alternative Peptide Names Sodium-Dependent Dopamine Transporter protein
Da Transporter protein
Dat protein
Solute Carrier Family 6 Member 3 protein
SLC6A3 protein
DAT1 protein

Information sourced from Uniprot.org

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