Host: |
Rabbit |
Applications: |
Immunodepletion/Immunocompetition |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Dopamine beta hydroxylase Blocking Peptide for STJ507829 is synthetically produced from the 125-178 sequence and is suitable for use in western blot applications. |
Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: |
Dbh |
Gene ID: |
13166 |
Uniprot ID: |
DOPO_MOUSE |
Immunogen Region: |
125-178 |
Specificity: |
This blocking peptide is recommended for use in combination with Dopamine beta hydroxylase antibody, STJ507829 |
Immunogen: |
Synthetic peptide taken within amino acid region 125-178 on mouse Dopamine beta hydroxylase. |
Post Translational Modifications | Proteolytic cleavage after the membrane-anchor leads to the release of the soluble form. N-glycosylated. |
Function | Catalyzes the hydroxylation of dopamine to noradrenaline (also known as norepinephrine), and is thus vital for regulation of these neurotransmitters. |
Peptide Name | Dopamine Beta-HydroxylaseDopamine Beta-Monooxygenase Cleaved Into - Soluble Dopamine Beta-Hydroxylase |
Database Links | Reactome: R-MMU-209905 |
Cellular Localisation | Soluble Dopamine Beta-Hydroxylase: Cytoplasmic VesicleSecretory Vesicle LumenCytoplasmic VesicleSecretory VesicleChromaffin Granule LumenSecretory Vesicle MembraneSingle-Pass Type Ii Membrane ProteinChromaffin Granule Membrane |
Alternative Peptide Names | Dopamine Beta-Hydroxylase proteinDopamine Beta-Monooxygenase Cleaved Into - Soluble Dopamine Beta-Hydroxylase proteinDbh protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance