| Applications: | Immunodepletion/Immunocompetition |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | DNER Blocking Peptide for STJ500779 is synthetically produced from the 700-737 sequence and is suitable for use in western blot applications. |
| Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Dilution Range: | WB: 1:2, 500-1:5, 000 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | DNER |
| Gene ID: | 92737 |
| Uniprot ID: | DNER_HUMAN |
| Immunogen Region: | 700-737 |
| Specificity: | This blocking peptide is recommended for use in combination with DNER antibody, STJ500779 |
| Immunogen: | Synthetic peptide taken within amino acid region 700-737 on human Delta and Notch-like Epidermal growth factor-related receptorprotein. |
| Tissue Specificity | Expressed in brain, spinal cord and adrenal gland. |
| Function | Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis. |
| Peptide Name | Delta And Notch-Like Epidermal Growth Factor-Related Receptor |
| Database Links | Reactome: R-HSA-2122948 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinPresent On The Membrane Of Dendrites And Cell Bodies But Excluded From Axonal MembraneAlso Found In Early Endosomes In The Somatodendritic Region |
| Alternative Peptide Names | Delta And Notch-Like Epidermal Growth Factor-Related Receptor proteinDNER proteinBET proteinUNQ262 proteinPRO299 protein |
Information sourced from Uniprot.org