Cynomolgus IL-23A&Mouse IL-12B protein (Recombinant) (N-His) (STJP020321)

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STJP020321
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Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation: Unconjugated
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: < 1 EU/Mu g of the protein by LAL method.
Immunogen Region: Val22-Pro189
Immunogen: Recombinant Cynomolgus IL-23A&Mouse IL-12B Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val22-Pro189 (Cynomolgus IL-23A) &Met23-Ser335 (Mouse IL-12B) ) of cynomolgus IL-23A&mouse IL-12B (Access
Background Interleukin (IL)-12 and IL-23 belong to the IL-12 type family and are composite cytokines, consisting of the common Beta subunit p40 and the specific cytokine Alpha subunit p35 and p19, respectively. IL-12 signals via the IL-12R Beta 1·IL-12R Beta 2 receptor complex, and IL-23 uses also IL-12R Beta 1 but engages IL-23R as second receptor.

Information sourced from Uniprot.org