| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from 0.22 Mu m filtered solution in PBS (pH 7.4). |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 0.1 EU/Mu g of the protein by LAL method. |
| Immunogen Region: | Lys208-Lys429 |
| Immunogen: | Recombinant Cynomolgus IgE Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Lys208-Lys429) of Cynomolgus IgE (Accession # G8F4W7) fused with His tag and Avi tag at the C-terminus. |
| Immunogen Sequence: | KCADSNPRGVSAYLSRPSPF DLFISKSPTITCLVVDLAPS KETVNLTWSRASGKPVPHIP ATEKKQQRNGTLTVTSILPV VTQDWIEGETYQCRVIHPHL PRALVRSMTKTSGPRAAPEV YVFATPEKLESRDKRTLACL IENFMPEDISVQWLHSDVQL PDTRHSVTQPRKTKGSGFFV FSRLEVTKAEWEQKDEFICR AVHEAASPSWIVQQAVSVNP GK |
| Background | IgE protein is an important immunoglobulin component that participates in the recognition and effector phases of humoral immunity. As a membrane-bound receptor on B lymphocytes, IgE triggers clonal expansion upon antigen binding, leading to plasma cell differentiation. |
Information sourced from Uniprot.org
