Cynomolgus Fc gamma RIIA/CD32a protein (Recombinant) (C-His) (STJP020275)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Cynomolgus Fc gamma RIIA/CD32a Protein is expressed from Expi293 with His tag at the C-terminal.οΌIt contains Gln28-Pro208.
General Information
| Short Description | Recombinant-Cynomolgus Fc gamma RIIA/CD32a-C-His protein was developed in hek293 cells using the region Gln28-Pro208. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Storage Instruction | Store at-20Β°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 1 EU/Mu g of the protein by LAL method. |
Target Information
| Immunogen | Recombinant Cynomolgus Fc gamma RIIA/CD32a Protein is expressed from Expi293 with His tag at the C-terminal.οΌIt contains Gln28-Pro208. |
| Immunogen Region | Gln28-Pro208 |
Additional Info
| Background | The Fc gamma Rs have been divided into three classes based on close relationships in their extracellular domains; these groups are designated Fc gamma RI (also known as CD64) , Fc gamma RII (CD32) , and Fc gamma RIII (CD16). Each group may be encoded by multiple genes and exist in different isoforms depending on species and cell type. The CD64 proteins are high affinity receptors (~10e-8-10e-9 M) capable of binding monomeric IgG, whereas the CD16 and CD32 proteins bind IgG with lower affinities (~10e-6-10e-7 M) only recognizing IgG aggregates surrounding multivalent antigens. |
Information sourced from Uniprot.org