| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 1 EU/Mu g of the protein by LAL method. |
| Immunogen Region: | Asp19-Thr256 |
| Immunogen: | Recombinant CynomolgusB7-H2/ICOSLG/CD275 Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Asp19-Thr256) of Cynomolgus B7-H2 fused with His tag at the C-terminus. |
| Background | B7-H2, also known as B7-related protein (B7RP1) , ICOS Ligand, and CD275, is an approximately 60 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. B7-H2 is a ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. |
Information sourced from Uniprot.org
